Can you believe it? Rally Foundation for Childhood Cancer Research just awarded $2 million in childhood cancer research grants. If you had...
$2 Million in Grants!
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Research
What is Langerhans Cell Histiocytosis (LCH)?
Langerhans cell histiocytosis (LCH) is a rare disorder in which the body produces an overabundance of Langerhans cells. These cells, which...
What is Lymphoma?
Lymphoma is a cancer of the body’s lymphatic (lymph) system which is essential to the immune system. The lymphatic system is made up of a...
What is Ependymoma?
Ependymoma is a tumor that appears most often in the brain and sometimes in the spinal cord. It is a type of glioma, meaning it starts in...
What is Chronic Myeloid Leukemia (CML)?
Chronic myeloid leukemia (CML) is a type of blood cancer that causes an overproduction of white blood cells. These cells grow abnormally...
Adjust, Readjust and Hope
By: Dean Crowe, Founder & CEO Last year, when COVID-19 hit, I thought about our Rally families and how they handle everything that is...
Rally Kid Keren’s Future Is Bright
Childhood cancer doesn’t just affect childhood. The effects of fighting cancer can last a lifetime. When you give to Rally, you help kids...
What is Ewing Sarcoma?
Ewing Sarcoma Defined Ewing sarcoma is a cancerous bone tumor that affects children, adolescent and young adults—usually developing during...
What is Atypical Teratoid/Rhabdoid Tumor (AT/RT)?
Atypical Teratoid/Rhabdoid Tumor (AT/RT) is a rare and fast-growing tumor that typically originates in the brain and spinal cord. These...
What is Diffuse Intrinsic Pontine Glioma (DIPG)?
Diffuse intrinsic pontine glioma (DIPG) is a brain tumor found in a part of the brain stem—above the back of the neck and connected to the...
Research
INSTRuCT Database for Rhabdomyosarcoma Impact
Rally is proud to be the initial funder for the creation of the INSTRuCT Database with a Consortium Grant to Dr. Sam Volchenboum of the Pediatric Cancer Data Commons (PCDC) at the University of Chicago. Recent advances in genomic medicine look promising in the study of rhabdomyosarcoma (RMS). RMS is a rare soft tissue malignancy primarily diagnosed before adolescence. RMS studies are historically challenged, given that only approximately 350 patients are diagnosed with RMS each year in the...
New RNA Therapies for Glioblastoma from Small Phase 1 Study
Glioblastoma (GBM) in children and adults is a deadly brain tumor with a poor prognosis. Current treatment includes surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Unfortunately, most patients still experience tumor growth despite the treatment and have a median survival of less than two years. Immunotherapy has shown success in the treatment of other types of tumors, but that success has been elusive with malignant brain tumors, such as GBM....
What is Big Data and Childhood Cancer Research
After being born and living in Turkey my whole life, I came to the US for college to study biological sciences at the University of Chicago. When the laboratory research internship I found for the summer of my first year was cancelled due to COVID-19, I joined a resume match program of my school’s Career Advancement Office, which matched students with employers based on experience and preferences. It was initially through this program that I matched with the Pediatric Cancer Data Commons...
AML Treatment Developments
Rally Foundation for Childhood Cancer Research is excited to announce new developments in the treatment of childhood acute myeloid leukemia (AML) emerging from research in the Meshinchi laboratory at the Fred Hutchinson Cancer Research Center (Fred Hutch) in Seattle. Immunotherapy is a type of treatment that harnesses the immune system to kill cancer cells. To avoid toxicity and unpleasant side effects of treatment, researchers search for molecules or a “target” on the surface of cancer cells...
The Spark Has Ignited A Fire: How Rally’s Seed Funding Paved the Way for Dr. Volchenboum and the PCDC
At Rally Foundation for Childhood Cancer Research, we often describe ourselves as “philanthropic seed investors in the next great discovery.” That’s because Rally invests early and continues to invest as projects make progress. It’s also because we like to take a few risks when it comes to funding the more “unconventional” research projects. After all, it only takes one spark to light a fire, and that spark—that next great discovery—could pave the way to finding a cure. Dr. Sam Volchenboum’s...
Building a Bridge: Expediating and Advancing Pediatric Brain Tumor Research
When to Build a New Bridge I love Rally. I love all the unique opportunities it provides—like building a bridge. Who knew? But first, a little background. A few weeks ago, my husband Reid and his good friend Marty built a bridge across the creek in our backyard. The landscape and topography around the creek changed through the years, and our low-profile bridge had washed away. So, to get to the other side of the creek, Reid would put on his waders and trudge across the water. It wasn’t very...