Success Stories

Rally Kid Keren is a True Advocate

Rally Kid Keren is a True Advocate

“I have been fighting cancer and the side effects since 2017,” shares Rally Kid Keren, who beat rhabdomyosarcoma almost five years before being diagnosed with a completely different cancer, osteosarcoma, in 2021. Dealing with this new cancer diagnosis has been a hard road for Keren and her family. They have found a way of understanding and coping with the harsh treatments and difficult procedures. Just ask for clarification. Keren’s mom Kelly proudly explains, “Keren has really learned how to be an advocate for herself. She is kind but clear when she asks to learn more. This is truly an amazing feat – many people much older than her do not wish, or do not know how to speak up when the doctor or nurse prescribes or implements a certain treatment or process. She really is an impressive role model. Keren empowers us, her parents, as well as other childhood cancer patients, to go ahead and...

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What is Charity Navigator?

What is Charity Navigator?

When you are in the market for a new refrigerator, you ask your neighbors and friends for recommendations, and maybe even consult Consumer Reports to see different ratings. When you want to donate to a charity, how do you decide if the charity will take care of your donation and use your donation to meet its mission? Charity Navigator has been called the Consumer Reports of the nonprofit world. It is the largest charity evaluator in America. Its website attracts more visitors than all other charity rating groups combined.  Charity Navigator is a free service that evaluates the financial health, accountability and transparency of more than 6,000 charities. Rally Foundation for Childhood Cancer Research (Rally) has a perfect score of 100 from Charity Navigator. “Less than one percent of the thousands of charities rated by Charity Navigator have earned perfect scores. We applaud these...

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$56 Million In New Federal Funding

$56 Million In New Federal Funding

ATLANTA (September 1, 2022) – After six years of intense advocacy with Department of Defense (DOD) Subcommittee members, Rally Foundation for Childhood Cancer Research is excited to announce $56 million in new federal funding this year for cancers affecting children, adolescents, and young adults (AYAs). The $56 million is being awarded from the DOD Congressionally Directed Medical Research Programs’ (CDMRP) Peer Reviewed Cancer Research Program directly to researchers, funding 44 projects. Rally Foundation’s Founder, Dean Crowe, who never stops looking for new funding, learned six years ago that the DOD has a $1.5 billion medical research program. At the time, about $300 million was allocated to cancers where the average age of diagnosis was 66 years old — even though almost 90% of active military personnel are 39 years old or younger with an average age of 25 years. In addition,...

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New and Innovative Study Technique for Osteosarcoma Metastasis

New and Innovative Study Technique for Osteosarcoma Metastasis

Osteosarcoma (OS) is a type of cancer that begins in the cells that form bones, and mainly affects teenagers and young adults. In metastatic osteosarcoma, the cancer spreads from the primary bone site to another location, most often the lungs. It can also spread to other bones, the brain or other organs. Currently there are no curative treatments for metastatic osteosarcoma. We urgently need to develop new therapies. To better understand a disease, it is common for tumor research studies to use orthotopic implantation. This method grafts tumor tissue where the disease begins in a mouse model. For osteosarcoma studies that would be in a bone allowing researchers to examine cancer progression more accurately and identify potential drug combinations more reliably. Rally-funded researcher Lindsay Jones Talbot, MD, is a pediatric surgeon, researcher, and instructor at St. Jude Children’s...

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INSTRuCT Database for Rhabdomyosarcoma Impact

INSTRuCT Database for Rhabdomyosarcoma Impact

Rally is proud to be the initial funder for the creation of the INSTRuCT Database with a Consortium Grant to Dr. Sam Volchenboum of the Pediatric Cancer Data Commons (PCDC) at the University of Chicago. Recent advances in genomic medicine look promising in the study of rhabdomyosarcoma (RMS). RMS is a rare soft tissue malignancy primarily diagnosed before adolescence.   RMS studies are historically challenged, given that only approximately 350 patients are diagnosed with RMS each year in the United States and around 700 patients a year in Western Europe. It is challenging to conduct clinical trials of anticancer drugs for the treatment of RMS due to the rarity, its various subtypes and differences in gene mutations. As a solution, the International Soft-Tissue Sarcoma Database Consortium (INSTRuCT) was created through collaboration with the Children’s Oncology Group (COG) Soft-Tissue...

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New RNA Therapies for Glioblastoma from Small Phase 1 Study

New RNA Therapies for Glioblastoma from Small Phase 1 Study

Glioblastoma (GBM) in children and adults is a deadly brain tumor with a poor prognosis. Current treatment includes surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Unfortunately, most patients still experience tumor growth despite the treatment and have a median survival of less than two years.  Immunotherapy has shown success in the treatment of other types of tumors, but that success has been elusive with malignant brain tumors, such as GBM. However, new ribonucleic acid (RNA) based immunotherapy is showing promise in treatment for GBM. Rally-funded researcher Elias Sayour, MD, PhD, and his team at the University of Florida recently published exciting discoveries focusing on the utilization of RNA dendritic cell (DC) vaccines and RNA nanoparticle therapies in the treatment of GBM. RNA-based therapies offer clear advantages over other...

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Success Stories

Rally Kid Keren is a True Advocate

Rally Kid Keren is a True Advocate

“I have been fighting cancer and the side effects since 2017,” shares Rally Kid Keren, who beat rhabdomyosarcoma almost five years before being diagnosed with a completely different cancer, osteosarcoma, in 2021. Dealing with this new cancer diagnosis has been a hard road for Keren and her family. They have found a way of understanding and coping with the harsh treatments and difficult procedures. Just ask for clarification. Keren’s mom Kelly proudly explains, “Keren has really learned how to...

read more
What is Charity Navigator?

What is Charity Navigator?

When you are in the market for a new refrigerator, you ask your neighbors and friends for recommendations, and maybe even consult Consumer Reports to see different ratings. When you want to donate to a charity, how do you decide if the charity will take care of your donation and use your donation to meet its mission? Charity Navigator has been called the Consumer Reports of the nonprofit world. It is the largest charity evaluator in America. Its website attracts more visitors than all other...

read more
$56 Million In New Federal Funding

$56 Million In New Federal Funding

ATLANTA (September 1, 2022) – After six years of intense advocacy with Department of Defense (DOD) Subcommittee members, Rally Foundation for Childhood Cancer Research is excited to announce $56 million in new federal funding this year for cancers affecting children, adolescents, and young adults (AYAs). The $56 million is being awarded from the DOD Congressionally Directed Medical Research Programs’ (CDMRP) Peer Reviewed Cancer Research Program directly to researchers, funding 44 projects....

read more
New and Innovative Study Technique for Osteosarcoma Metastasis

New and Innovative Study Technique for Osteosarcoma Metastasis

Osteosarcoma (OS) is a type of cancer that begins in the cells that form bones, and mainly affects teenagers and young adults. In metastatic osteosarcoma, the cancer spreads from the primary bone site to another location, most often the lungs. It can also spread to other bones, the brain or other organs. Currently there are no curative treatments for metastatic osteosarcoma. We urgently need to develop new therapies. To better understand a disease, it is common for tumor research studies to...

read more
INSTRuCT Database for Rhabdomyosarcoma Impact

INSTRuCT Database for Rhabdomyosarcoma Impact

Rally is proud to be the initial funder for the creation of the INSTRuCT Database with a Consortium Grant to Dr. Sam Volchenboum of the Pediatric Cancer Data Commons (PCDC) at the University of Chicago. Recent advances in genomic medicine look promising in the study of rhabdomyosarcoma (RMS). RMS is a rare soft tissue malignancy primarily diagnosed before adolescence.   RMS studies are historically challenged, given that only approximately 350 patients are diagnosed with RMS each year in the...

read more
New RNA Therapies for Glioblastoma from Small Phase 1 Study

New RNA Therapies for Glioblastoma from Small Phase 1 Study

Glioblastoma (GBM) in children and adults is a deadly brain tumor with a poor prognosis. Current treatment includes surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Unfortunately, most patients still experience tumor growth despite the treatment and have a median survival of less than two years.  Immunotherapy has shown success in the treatment of other types of tumors, but that success has been elusive with malignant brain tumors, such as GBM....

read more

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