What Is

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What Is

What is Big Data and Childhood Cancer Research

What is Big Data and Childhood Cancer Research

After being born and living in Turkey my whole life, I came to the US for college to study biological sciences at the University of Chicago. When the laboratory research internship I found for the summer of my first year was cancelled due to COVID-19, I joined a resume match program of my school’s Career Advancement Office, which matched students with employers based on experience and preferences. It was initially through this program that I matched with the Pediatric Cancer Data Commons...

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Discovering the Reality of Childhood Cancer Treatment

Discovering the Reality of Childhood Cancer Treatment

On our diagnosis day, we were told that our four-year-old Gus had Ewing Sarcoma. What doctors didn’t know was the particular type or variant he had. Tumor Sequencing Tumor sequencing is vital, as some variants of Ewing’s sarcomas have poorer outcomes, require specific drugs, and prohibit the use of other drugs. The variant determines the treatment plan. Parents need to know the type of cancer their child is fighting- and if the hospital doesn’t know, parents should demand to have the tumor...

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What is an Astrocytoma?

What is an Astrocytoma?

An astrocytoma is a brain tumor that begins in astrocytes—a type of glial cell that supports nerve cells in the brain. Astrocytomas can be benign or malignant and typically occur in the brainstem, cerebellum, cerebrum, hypothalamus or optic nerves. Tumors that start in glial cells are called gliomas and are named for the specific kind of glial cell in which they originate: astrocytes, oligodendrocytes or ependymocytes. Astrocytomas are the most common form of gliomas found in...

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What is Langerhans Cell Histiocytosis (LCH)?

What is Langerhans Cell Histiocytosis (LCH)?

Langerhans cell histiocytosis (LCH) is a rare disorder in which the body produces an overabundance of Langerhans cells. These cells, which are also known as histiocytes, are a type of white blood cell that helps the immune system fight off infections. LCH causes too many of these cells to form, ultimately resulting in a buildup in the body. This accumulation of cells then damages organs, forms tumors, and otherwise disrupts normal tissue functions. According to the Histiocytosis Association,...

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What is Lymphoma?

What is Lymphoma?

Lymphoma is a cancer of the body’s lymphatic (lymph) system which is essential to the immune system. The lymphatic system is made up of a type of white blood cells also known as lymphocytes which flow throughout the whole body. These lymphocytes fight infections throughout the body, so when cancerous cells begin to grow they can quickly spread through the entire lymph system. This then makes it difficult for the immune system to work properly. Early symptoms of lymphomas usually begin with a...

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What is Ependymoma?

What is Ependymoma?

Ependymoma is a tumor that appears most often in the brain and sometimes in the spinal cord. It is a type of glioma, meaning it starts in the support cells of the brain. This cancer occurs more frequently in children—accounting for 5-10% of all pediatric brain tumors—but it can also affect adults. Common pediatric subtypes include classic ependymoma, a tumor that most commonly appears in the brain, and anaplastic ependymoma, which tends to spread and has a high chance of recurrence. Each type...

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