Rally-Funded Discoveries

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Rally-Funded Discoveries

From Idea to Clinical Trial: How Dr. David Loeb’s Research Is Changing Childhood Cancer Treatment

From Idea to Clinical Trial: How Dr. David Loeb’s Research Is Changing Childhood Cancer Treatment

Dr. David Loeb, M.D., Ph.D., from the Montefiore Einstein Comprehensive Cancer Center, has dedicated his career to finding better treatments for children with sarcoma, a type of childhood cancer. Early support from Rally Foundation helped him take the first big steps in his research journey. In 2012, Dr. Loeb received his first Rally grant. This funding helped him study how Ewing sarcoma cancer cells use energy differently than healthy cells. Those first experiments led to important...

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How Rally’s Early Support Helped Launch a Surgeon’s Mission to Defeat Childhood Cancer

How Rally’s Early Support Helped Launch a Surgeon’s Mission to Defeat Childhood Cancer

When Eric Rellinger, M.D., was training to become a surgeon at Vanderbilt University Medical Center, he became fascinated by how cancer cells survive. He realized that cancers keep growing because they constantly demand more building blocks inside the body, helping them resist treatments that are meant to stop them. His first research project studied special enzymes called NADPH oxidases in neuroblastoma, a very aggressive type of childhood cancer. These enzymes help produce molecules that...

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The Power of Seed Funding: Dr. Kevin Bunting’s Breakthroughs in Pediatric AML Research

The Power of Seed Funding: Dr. Kevin Bunting’s Breakthroughs in Pediatric AML Research

When we first met Kevin Bunting, Ph.D., from Emory University, we saw a scientist with big ideas and bold goals. His work focused on finding new ways to fight acute myeloid leukemia (AML), one of the most aggressive forms of childhood cancer. Rally Foundation for Childhood Cancer Research was the first organization to believe in his vision, providing seed funding for two early projects. That early support helped Dr. Bunting and his team focus on a protein called STAT5. When STAT5 is activated,...

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Turning Data Into Hope: Rally’s Impact on Pediatric Brain Tumor Research

Turning Data Into Hope: Rally’s Impact on Pediatric Brain Tumor Research

Since 2022, Rally Foundation for Childhood Cancer Research has played a key role in helping Adam Resnick, Ph.D., at Children’s Hospital of Philadelphia and the Children’s Brain Tumor Network advance their mission to find better treatments for kids with brain tumors. Rally Foundation’s support has helped grow this global effort by expanding access to data, improving research tools, and fueling discoveries that bring hope to families everywhere. The Children’s Brain Tumor Network is a group of...

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The Heart of Survivorship: How Rally Funding Helped Prevent Heart Failure in Childhood Cancer Survivors

The Heart of Survivorship: How Rally Funding Helped Prevent Heart Failure in Childhood Cancer Survivors

For many kids who beat cancer, the battle does not end when treatment does. Years later, they can face new health challenges caused by the very treatments that saved their lives. One of the most serious is heart failure, a condition that can quietly develop over time and deeply affect survivors’ health and quality of life. That is why early research to prevent it is so critical.  With early support from the Rally Foundation for Childhood Cancer Research, Saro Armenian, D.O., MPH, from City of...

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Fighting Osteosarcoma with a Bold Idea

Fighting Osteosarcoma with a Bold Idea

When Lily Guenther, M.D., was just starting her career in childhood cancer research at Dana-Farber Cancer Institute, Rally Foundation for Childhood Cancer Research gave her something big, support to chase a bold idea. She was studying osteosarcoma, a rare and aggressive bone cancer that mostly affects kids and teens. It’s especially hard to treat when it spreads to other parts of the body. This is called metastatic cancer, and sadly, many kids already have metastatic osteosarcoma when they’re...

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