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Langerhans cell histiocytosis (LCH) is a rare disorder in which the body produces an overabundance of Langerhans cells. These cells, which are also known as histiocytes, are a type of white blood cell that helps the immune system fight off infections. LCH causes too many of these cells to form, ultimately resulting in a buildup in the body. This accumulation of cells then damages organs, forms tumors, and otherwise disrupts normal tissue functions. According to the Histiocytosis Association,...
Lymphoma is a cancer of the body’s lymphatic (lymph) system which is essential to the immune system. The lymphatic system is made up of a type of white blood cells also known as lymphocytes which flow throughout the whole body. These lymphocytes fight infections throughout the body, so when cancerous cells begin to grow they can quickly spread through the entire lymph system. This then makes it difficult for the immune system to work properly. Early symptoms of lymphomas usually begin with a...
Ependymoma is a tumor that appears most often in the brain and sometimes in the spinal cord. It is a type of glioma, meaning it starts in the support cells of the brain. This cancer occurs more frequently in children—accounting for 5-10% of all pediatric brain tumors—but it can also affect adults. Common pediatric subtypes include classic ependymoma, a tumor that most commonly appears in the brain, and anaplastic ependymoma, which tends to spread and has a high chance of recurrence. Each type...
Chronic myeloid leukemia (CML) is a type of blood cancer that causes an overproduction of white blood cells. These cells grow abnormally and can build up in the blood and bone marrow, leaving less room for healthy white and red blood cells as well as platelets. CML is commonly associated with a genetic mutation called the Philadelphia chromosome. While CML is very rare in children, with about 150 pediatric cases in the U.S. each year, it’s often more aggressive in kids than it is in adults....
By: Dean Crowe, Founder & CEO Last year, when COVID-19 hit, I thought about our Rally families and how they handle everything that is thrown at them—which is a lot. Over and over, I have watched them adjust and readjust. Trying to learn from the best, I drew inspiration from these brave people in 2020. "Adjust and readjust” became my personal mantra and Rally’s theme for the year. Adjust and readjust we did. I have to be honest; it is a good game plan. It served Rally exceptionally well,...
Thank you for opening this letter. And for caring about kids fighting cancer. What a year. We can all agree that 2020 is not a year we will soon forget. When the pandemic struck, I thought about the Rally Kids and their families. Their “normal” is living with an immunocompromised child, yet I have always been inspired and in awe of their ability to adjust and readjust. So personally, and at Rally, I took my cue from them. Our theme became adjust and readjust. And that is what we did. Like many...