Jason T. Yustein, MD, PHD

Baylor College of Medicine; Houston, TX – Assistant Professor, Department of Pediatrics

Dr. Jason Yustein’s research interests include furthering the biological, molecular and genetic understanding of pediatric sarcomas, including osteosarcoma and Ewing’s sarcoma, through the formation of novel model systems that will lead to the discovery of new therapeutic targets and subsequent development of new treatment interventions. For example, Dr. Yustein is utilizing osteoblast-specific expression of an oncogenic p53 mutant to form a novel, applicable transgenic mouse model of metastatic osteosarcoma, a condition that has a particularly poor prognosis. Such models will allow for further understanding of critical genes and microRNAs involved in sarcoma development, progression and metastasis and utilized as preclinical models for therapeutic testing and efficacy. Dr. Yustein is Director of the Faris D. Virani Ewing Sarcoma Center and a member of the Bone Tumor Program.