Casey Langdon, PHD

Medical University of South Carolina Children’s Hospital – Assistant Professor

Dr. Langdon is an Assistant Professor in the Department of Pediatrics and a Member of both the Darby Children’s Research Institute and Hollings Cancer Center at the Medical University of South Carolina. The goal of the Langdon laboratory is to find less toxic and more effective targeted therapies for oncogenic fusion transcription factor-driven pediatric sarcomas. This includes the second most common pediatric bone cancer, Ewing sarcoma.
Dr. Langdon received his PhD training in Dr. David Stern’s laboratory at Yale University. His dissertation research consisted of using combination drug screens to nominate new dual inhibitor therapies for difficult to treat adult malignancies. These cancers included melanoma as well as lung and pancreatic cancers. His postdoctoral training was in the laboratory of Dr. Mark Hatley at St. Jude Children’s Research Hospital. In Dr. Hatley’s lab, Dr. Langdon studied how genetic alterations observed in fusion-negative rhabdomyosarcoma patients contributed to tumorigenesis in both murine and human models.