St. Jude Children’s Research Hospital – Member; Director, Experimental Hematology

Dr. Crispino is the Director of the Division of Experimental Hematology at St. Jude Children’s Research Hospital. Previously, Dr. Crispino was the Associate Director of Education and Training at the Robert H. Lurie Comprehensive Cancer Center at the Feinberg School of Medicine in Chicago, IL as well as a Lora S Lurie Professor of Medicine. Dr. Crispino studies the biology of normal and malignant blood cell development. In 2002, his team discovered that GATA1 mutations are associated with acute megakaryocytic leukemia in children with Down syndrome. Since that time, his laboratory has focused on understanding why children with DS face an increased risk of both myeloid and lymphoid leukemia and on developing improved therapies for the malignancies.

Dr. Crispino earned his PhD in Biology from the Massachusetts Institute of Technology and completed a postdoctoral fellowship at Boston Children’s Hospital before launching his own innovative research program at the University of Chicago. He then moved his laboratory to Northwestern University, where he also earned his MBA from the Kellogg School of Management.

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