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Rally Success Stories

Childrens Hospital LA
  • Phase II Clinical Trial on relapsed and refractory Acute Lymphoblastic Leukemia
  • 16 patients have been enrolled, plan to enroll 3 more in next few months
  • Had insufficient funds to complete this study prior to receiving Rally’s grant

Children’s Healthcare of Atlanta
  • Supporting a Bone Marrow Transplant Clinical Research Nurse who has worked with 45 new patients this year
  • Supporting the collection of tissue samples for a tumor bank and associated research
  • Supporting the collection of DNA samples and long-term survivor follow-up data
    • 263 patients have been enrolled since receiving funds from Rally in March 2009
    • 473 DNA specimens have been collected
    • 288 baseline surveys have been collected from long-term survivors

Children’s Hospital Philadelphia
  • Studying genetic mutations in neuroblastoma
  • Have re-sequenced 118 genes in 188 tumors and confirmed each genetic mutation in separate experiments
  • Identifying pathways of these genetic pathways so that they can be targeted for treatment
  • Related research at CHOP was recently featured in news as boosting 2 year survival rate by 20%

Cleveland Clinic
  • Supporting a Phase II Clinical Trial on pediatric patients with progressive or recurrent low-grade glioma
  • Study is now open and enrolling its first 2 patients

Columbia University
  • Studying genetic influence in T-cell Acute Lymphoblastic Leukemia
  • Preliminary results link the functions of a specific protein with genetic control and DNA repair
  • Observed that manipulation of this protein causes some T-ALL cells to become sensitive to chemotherapy

Children's Oncology Group
  • Supporting the Childhood Cancer Research Network, which enrolls patients to obtain info and follow them in the future to study epidemiology and late effects of treatment
  • 16,647 patients have enrolled since December 2007

Medical University of South Carolina
  • Researching how the changing the amounts and/or types of specific proteins control the growth of neuroblastoma
  • Measuring the protein levels in tumor samples with the goal of developing new targeted therapies
  • Preliminary results show increased protein levels in high risk patients, now researchers are confirming these findings with a larger sample size

Pediatric Cancer Foundation
  • The Sunshine Project is a coalition of the nation’s leading pediatric oncologists, pathologists, biologists and medical information technology specialists who collaborate in an effort to find less toxic, more targeted treatments for pediatric cancer.

Seattle Children’s Hospital
  • Providing resources and support for childhood cancer survivors
  • Funding DNA saliva collection kits for a study researching fertility in childhood cancer survivors